Basic Periactin Information

• International Nonproprietary Name (INN): Cyproheptadine
• Brand Names Available in Australia: Periactin, among others
• ATC Code: R06AX02
• Forms & Dosages: Tablets (4 mg), Syrup (2 mg/5 ml)
• Manufacturers in Australia: Viatris Pty Ltd
• Registration Status in Australia: AUST R 62384
• OTC / Rx Classification: Available Over-the-Counter (OTC)

Everyday Use & Best Practices

Fitting Periactin into daily routines can play a significant role in managing allergies, stimulating appetite, or addressing other concerns. ### Morning vs Evening Dosing (Australian Daily Routines) For many Australians, how and when to take Periactin hinges on daily schedules. - **Morning Dosing Benefits** - Taking Periactin in the morning might complement active lifestyles as users can leverage its antihistamine effects throughout the day. - A morning dose can help mitigate seasonal allergies, making outdoor activities more enjoyable. - **Evening Dosing Advantages** - For those dealing with sleep issues or needing to counteract side effects like drowsiness, an evening dose may be beneficial. - Evening doses might also align with the body’s circadian rhythms, enhancing effectiveness for nighttime discomfort. When considering morning versus evening dosing, effectiveness and side effects should guide the choice. Consult with a healthcare professional for personalised advice on timing based on lifestyle and medical conditions. ### Taking With or Without Meals Food can dramatically influence how well Periactin works. - **Absorption Affected by Food** - Taking Periactin on an empty stomach is generally seen to enhance absorption, potentially leading to quicker onset of its antihistamine effects. - On the flip side, consuming Periactin with meals may reduce stomach discomfort — a common concern for many users. - **Practical Advice** - If you're sensitive to stomach irritation, try taking it with food. - For those prioritising effectiveness, consider taking it before meals for optimal absorption. Monitoring personal responses to different dosing methods can help determine which approach suits best. Adjusting the timing and method of intake can significantly enhance the user experience with this medication. Overall, understanding how to integrate Periactin into daily life makes it easier to manage symptoms effectively. Whether adjusting dosing times or meal considerations, there’s a strategic way to maximise benefits with minimal side effects. Always double-check with a health professional for tailored advice suited to individual needs.

Buying Guide

When looking to purchase Periactin, knowing where to start can help save time and money. Here are the major Australian pharmacy chains where this antihistamine is available:

• Chemist Warehouse
• Priceline
• TerryWhite Chemmart

To find good deals and check availability online:

• Compare prices across these stores. Many have online platforms that reflect real-time stock.
• Look for special promotions or discounts on bulk purchases.
• Sign up for newsletters for notifications on sales and promotions.

Price comparison

Prices for Periactin can vary significantly, especially between PBS-subsidised and private purchases. While the Pharmaceutical Benefits Scheme (PBS) provides subsidies for eligible patients, private purchases can be higher.

To navigate PBS guidelines for the best deal:

• Consult your doctor to check if you meet the PBS criteria.
• Always ask your pharmacist about the PBS price and make sure you’re purchasing the correct version for your needs.

What’s Inside & How It Works

Ingredients overview

The active ingredient in Periactin is cyproheptadine, an antihistamine that’s effective in relieving allergy symptoms and stimulating appetite. Excipients found in this medication may vary but typically include agents that help with tablet stability and absorption.

Mechanism basics explained simply

Periactin works mainly by blocking histamine receptors in the body which helps alleviate allergy symptoms like itching and runny nose. Additionally, it enhances appetite by acting on the central nervous system, making it useful for individuals needing to gain weight.

Main Indications

Approved uses under TGA

Australia's Therapeutic Goods Administration (TGA) has approved Periactin for several uses, primarily:

• Allergic reactions, including hay fever
• Appetite stimulation
• Preventing migraines (though this is often off-label)

Off-label uses in Australian clinics

In various Australian clinical settings, Periactin is commonly used off-label to stimulate appetite in children with chronic illnesses or those experiencing substantial weight loss.

Interaction Warnings

Food interactions

Certain foods and beverages can interact with Periactin:

- Alcohol may enhance drowsiness caused by Periactin, so it's advisable to avoid drinking.

- Coffee and energy drinks could counteract its sedative effects, making it harder to sleep if used for that purpose.

Understanding these interactions within the Australian diet is essential for safe use.

Drug conflicts tracked by TGA & PBS

TGA and PBS have documented key drug interactions. Medications that may conflict with Periactin include:

• Monoamine oxidase inhibitors (MAOIs)
• Antidepressants
• Other central nervous system depressants

It's crucial to discuss all medications with a healthcare provider to avoid adverse effects.

Latest Evidence & Insights

Recent studies from Australia and abroad (2022–2025) have examined the usage and effectiveness of Periactin (cyproheptadine). Clinical findings indicate its efficacy in treating allergic reactions and its off-label use for stimulating appetite in patients with cachexia and other conditions. New insights highlight Periactin's potential in managing certain migraine cases, although additional research is still needed to solidify these findings.

Several international studies have also delved into the safety of cyproheptadine. Notably, concerns regarding its sedative effects lead to recommendations for close monitoring in elderly patients and those with certain medical conditions. The medication's side effects, while generally manageable, include drowsiness, dry mouth, and potential for weight gain, especially in paediatric applications. Thus, healthcare providers continue to seek a balanced view of its benefits against potential risks.

Alternative Choices

When considering alternatives to Periactin, it's essential to weigh comparable medicines like loratadine and cetirizine. These alternatives are also popular antihistamines but differ in safety profiles, effectiveness, and side effects.

• Loratadine:
• Pros: Non-sedating, once-daily dosing, effective for allergy symptoms.
• Cons: May not be effective for everyone, not suitable for acute reactions.
• Cetirizine:
• Pros: Fast-acting, effective for allergy relief, and helps with hay fever.
• Cons: Can cause drowsiness in some individuals, potential weight gain.

Patients should consider these factors and consult healthcare professionals for personalized advice on antihistamines.

Regulation Snapshot

Periactin is registered with the Therapeutic Goods Administration (TGA) in Australia under AUST R 62384, confirming its safety and efficacy for prescribed uses. The drug is available both over the counter (OTC) and via prescription, depending on the indication for use.

As part of the Pharmaceutical Benefits Scheme (PBS), Periactin is subsidized for specific medical conditions, ensuring affordability for patients who require it for allergy management, appetite stimulation, or other approved uses. This framework promotes accessibility, allowing Australian patients to obtain the medication more readily without a hefty price tag.

FAQ Section

Is Periactin available over the counter in Australia?
Yes, Periactin can be purchased without a prescription in pharmacies. However, consultation with a pharmacist is recommended.

What is the proper dosage for adults?
The standard dosage for adult patients is typically 4 mg, taken three times a day, but this may vary based on the individual's condition and response.

How safe is Periactin for children?
While Periactin can be prescribed for children, especially for appetite enhancement, it should be administered under a healthcare provider's guidance due to possible side effects.

Can Periactin cause weight gain?
Yes, one of the known side effects of Periactin is increased appetite which may lead to weight gain in some patients.

Guidelines for Proper Use

During pharmacist consultations, patients can anticipate a friendly discussion about their symptoms, dosage recommendations, and any concerns regarding the use of Periactin. Pharmacists are well-equipped to provide guidance tailored to individual health profiles.

According to the PBS and national health authorities, key guidelines include:

• Using Periactin primarily for its approved indications.
• Monitoring for side effects, particularly sedation in vulnerable populations.
• Regular follow-ups for assessing the medication's effectiveness and patient well-being.

Such precautionary practices ensure that patients benefit from the medication while minimizing potential risks.

City	Region	Delivery Time
Sydney	NSW	5–7 days
Melbourne	VIC	5–7 days
Brisbane	QLD	5–7 days
Perth	WA	5–7 days
Adelaide	SA	5–7 days
Canberra	ACT	5–9 days
Hobart	TAS	5–9 days
Darwin	NT	5–9 days
Gold Coast	QLD	5–7 days
Newcastle	NSW	5–7 days
Cairns	QLD	5–9 days
Wollongong	NSW	5–9 days
Geelong	VIC	5–9 days
Sunshine Coast	QLD	5–9 days
Central Coast	NSW	5–9 days